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"Quienes" is a form of "quienes", a pronoun which is often translated as "who". "Los que" is a phrase which is often translated as "the ones that". Learn more about the difference between "quienes" and "los que" below.
quienes()
A pronoun is a word that stands in for a noun (e.g., she).
1. (relative)
2. (indefinite)
a. whoever
Felicito a quienes hayan participado en el concurso.Congratulations to whoever participated in the contest.
los que
A phrase is a group of words commonly used together (e.g., once upon a time).
a. the ones that
¿Ves esos trofeos? Son los que gané el año pasado.Do you see those trophies over there? Those are the ones that I won last year.
b. the ones who (people)
Mario y Armando son los que organizaron la fiesta.Mario and Armando are the ones who organized the party.